Peptide methionine sulfoxide reductase MsrA

BE0001618ProteinShigella flexnerimsrA

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. It is acted on by 1 drug in DrugBank.

Gene name
msrA
UniProtKB entry
P0A745Swiss-Prot
Residues / weight
212 residues · 23,315 Da
Also known as
1.8.4.11 · Peptide Met(O) reductase · Peptide-methionine (S)-S-oxide reductase · pms · Protein-methionine-S-oxide reductase

Resolves to

Protein
UniProtP0A745UniProt nameMSRA_SHIFL
Gene
NCBI Gene1026808GenBank24054789
Pharmacology
KEGGsfl:SF4268
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide methionine sulfoxide reductase MsrA, and which indications are they being tested in?

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