Sialidase

BE0001621ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)nanH

Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. It is acted on by 1 drug in DrugBank.

Gene name
nanH
UniProtKB entry
P29768Swiss-Prot
Residues / weight
382 residues · 42,073 Da
Also known as
3.2.1.18 · N-acylneuraminate glycohydrolase · NANase · Neuraminidase · STNA

Resolves to

Protein
UniProtP29768UniProt nameNANH_SALTY
Gene
NCBI Gene1252447GenBank531224
Pharmacology
KEGGstm:STM0928
Structure
PDB1DILPDB1DIMPDB2SIL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sialidase, and which indications are they being tested in?

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