Matrix metalloproteinase-16

BE0001637ProteinHumansMMP16

Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. It is acted on by 2 drugs in DrugBank.

Gene name
MMP16
UniProtKB entry
P51512Swiss-Prot
Cellular location
Cell membrane
Residues / weight
607 residues · 69,521 Da
Also known as
3.4.24.- · C8orf57 · Membrane-type matrix metalloproteinase 3 · Membrane-type-3 matrix metalloproteinase · MMP-16

Resolves to

Protein
UniProtP51512UniProt nameMMP16_HUMAN
Gene
HGNCHGNC:7162NCBI Gene4325GenBank2662306GeneCardsMMP16
Pharmacology
IUPHAR/GtoPdb1640KEGGhsa:4325
Structure
PDB1RM8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Matrix metalloproteinase-16, and which indications are they being tested in?

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