Sialic acid-binding Ig-like lectin 7

BE0001648ProteinHumansSIGLEC7

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It is acted on by 1 drug in DrugBank.

Gene name
SIGLEC7
UniProtKB entry
Q9Y286Swiss-Prot
Cellular location
Membrane
Residues / weight
467 residues · 51,142 Da
Also known as
Adhesion inhibitory receptor molecule 1 · AIRM-1 · AIRM1 · CDw328 · D-siglec

Resolves to

Protein
UniProtQ9Y286UniProt nameSIGL7_HUMAN
Gene
HGNCHGNC:10876NCBI Gene27036GenBank6466012GeneCardsSIGLEC7
Pharmacology
KEGGhsa:27036
Structure
PDB1NKOPDB1O7SPDB1O7V
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sialic acid-binding Ig-like lectin 7, and which indications are they being tested in?

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