Peptide deformylase

BE0001651ProteinStaphylococcus aureus (strain MW2)def

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 2 drugs in DrugBank.

Gene name
def
UniProtKB entry
Q8NX78Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
183 residues · 20,559 Da
Also known as
3.5.1.88 · def1 · PDF · pdf1 · Polypeptide deformylase

Resolves to

Protein
UniProtQ8NX78UniProt nameDEF_STAAW
Gene
NCBI Gene23196868GenBank21204141
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase, and which indications are they being tested in?

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