Threonine-phosphate decarboxylase

BE0001652ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)cobD

Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. It is acted on by 2 drugs in DrugBank.

Gene name
cobD
UniProtKB entry
P97084Swiss-Prot
Residues / weight
364 residues · 40,765 Da
Also known as
4.1.1.81 · L-threonine-O-3-phosphate decarboxylase

Resolves to

Protein
UniProtP97084UniProt nameCOBD_SALTY
Gene
NCBI Gene1252164GenBank1895094
Pharmacology
KEGGstm:STM0644
Structure
PDB1LC5PDB1LC7PDB1LC8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Threonine-phosphate decarboxylase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In