Regulatory protein BlaR1

BE0001655ProteinStaphylococcus aureusblaR1

Integral membrane protein involved in sensing of the presence of beta-lactam antibiotics and transduction of the information to the cytoplasm. It is acted on by 2 drugs in DrugBank.

Gene name
blaR1
UniProtKB entry
P18357Swiss-Prot
Cellular location
Cell membrane
Residues / weight
585 residues · 69,245 Da

Resolves to

Protein
UniProtP18357UniProt nameBLAR_STAAU
Gene
GenBank46758
Structure
PDB1XA1PDB1XA7PDB1XKZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Regulatory protein BlaR1, and which indications are they being tested in?

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