dTDP-4-dehydrorhamnose 3,5-epimerase

BE0001669ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)rfbC

Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. It is acted on by 1 drug in DrugBank.

Gene name
rfbC
UniProtKB entry
P26394Swiss-Prot
Residues / weight
183 residues · 20,663 Da
Also known as
5.1.3.13 · dTDP-4-keto-6-deoxyglucose 3,5-epimerase · dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase · dTDP-L-rhamnose synthase · rmlC

Resolves to

Protein
UniProtP26394UniProt nameRMLC_SALTY
Gene
NCBI Gene1253615GenBank581655
Pharmacology
KEGGstm:STM2094
Structure
PDB1DZRPDB1DZT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on dTDP-4-dehydrorhamnose 3,5-epimerase, and which indications are they being tested in?

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