Adenosylhomocysteinase

BE0001684ProteinHumansAHCY

Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798). It is acted on by 4 drugs in DrugBank.

Gene name
AHCY
UniProtKB entry
P23526Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
432 residues · 47,716 Da
Also known as
3.13.2.1 · AdoHcyase · S-adenosyl-L-homocysteine hydrolase · SAHH

Resolves to

Protein
UniProtP23526UniProt nameSAHH_HUMAN
Gene
HGNCHGNC:343NCBI Gene191GenBank178277GeneCardsAHCY
Pharmacology
IUPHAR/GtoPdb1233KEGGhsa:191
Structure
PDB1A7APDB1LI4PDB3NJ4
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adenosylhomocysteinase, how selective are they, and which programs against it are still in active trials?

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