3-dehydroquinate dehydratase

BE0001690ProteinStaphylococcus aureus (strain MRSA252)aroD

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. It is acted on by 1 drug in DrugBank.

Gene name
aroD
UniProtKB entry
Q6GII7Swiss-Prot
Residues / weight
238 residues · 27,053 Da
Also known as
3-dehydroquinase · 4.2.1.10 · DHQ1 · Type I dehydroquinase · Type I DHQase

Resolves to

Protein
UniProtQ6GII7UniProt nameAROD_STAAR
Gene
GenBank49241190
Pharmacology
KEGGsar:SAR0860
Structure
PDB1SFJPDB1SFL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-dehydroquinate dehydratase, and which indications are they being tested in?

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