3-dehydroquinate synthase

BE0001691ProteinStaphylococcus aureus (strain MRSA252)aroB

Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). It is acted on by 1 drug in DrugBank.

Gene name
aroB
UniProtKB entry
Q6GGU4Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
354 residues · 40,285 Da
Also known as
4.2.3.4 · DHQS

Resolves to

Protein
UniProtQ6GGU4UniProt nameAROB_STAAR
Gene
GenBank49241783
Pharmacology
KEGGsar:SAR1476
Structure
PDB1XAGPDB1XAHPDB1XAI
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-dehydroquinate synthase, and which indications are they being tested in?

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