Aminomethyltransferase
Details
- Name
- Aminomethyltransferase
- Kind
- protein
- Synonyms
- 2.1.2.10
- Glycine cleavage system T protein
- Gene Name
- gcvT
- UniProtKB Entry
- Q9WY54Swiss-Prot
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- NCBI Taxonomy ID
- 243274
- Amino acid sequence
>lcl|BSEQ0019166|Aminomethyltransferase MKRTPLFEKHVELGAKMVDFAGWEMPLYYTSIFEEVMAVRKSVGMFDVSHMGEFLVKGPE AVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALMVVNAANIEKDF NWIKSHSKNFDVEVSNISDTTALIAFQGPKAQETLQELVEDGLEEIAYYSFRKSIVAGVE TLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLGARDVCRLEATYLLYG QDMDENTNPFEVGLSWVVKLNKDFVGKEALLKAKEKVERKLVALELSGKRIARKGYEVLK NGERVGEITSGNFSPTLGKSIALALVSKSVKIGDQLGVVFPGGKLVEALVVKKPFYRGSV RREV
- Number of residues
- 364
- Molecular Weight
- 40332.235
- Theoretical pI
- 5.23
- GO Classification
- Functionsaminomethyltransferase activity / transaminase activityProcessesglycine decarboxylation via glycine cleavage system
- General Function
- The glycine cleavage system catalyzes the degradation of glycine.
- Specific Function
- aminomethyltransferase activity
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0019167|Aminomethyltransferase (gcvT) ATGAAGAGAACGCCTCTATTTGAAAAGCATGTTGAACTCGGTGCGAAAATGGTAGATTTC GCGGGGTGGGAGATGCCTCTTTATTACACATCCATATTCGAAGAAGTGATGGCAGTCAGA AAATCGGTGGGGATGTTCGATGTCTCTCACATGGGGGAATTTCTCGTTAAAGGGCCCGAG GCGGTTTCTTTTATTGACTTTCTTATAACGAACGACTTTTCTTCACTTCCGGATGGTAAA GCGATTTACTCTGTCATGTGCAATGAAAACGGTGGAATCATCGATGATCTTGTTGTGTAC AAGGTGAGTCCTGATGAAGCTCTCATGGTGGTGAACGCGGCAAACATTGAAAAGGACTTC AACTGGATAAAATCCCATTCGAAGAATTTCGATGTCGAAGTATCGAACATTTCAGATACG ACAGCGCTCATAGCGTTCCAGGGGCCAAAAGCACAGGAGACCCTCCAGGAGCTTGTTGAA GACGGTCTCGAGGAAATTGCCTATTATTCTTTCAGAAAGAGTATTGTAGCCGGTGTAGAG ACTCTTGTCTCAAGAACGGGATACACGGGTGAGGACGGTTTCGAACTGATGCTTGAAGCG AAGAATGCACCGAAGGTCTGGGATGCTTTGATGAATCTGCTCAGAAAAATCGATGGCAGA CCCGCAGGTCTTGGGGCGAGAGACGTTTGCCGACTCGAGGCGACTTATTTGCTGTACGGT CAGGACATGGATGAGAACACGAATCCTTTCGAAGTGGGACTTTCCTGGGTTGTAAAACTG AACAAAGACTTCGTGGGGAAGGAAGCGCTGCTGAAAGCGAAGGAAAAAGTGGAAAGAAAA CTTGTGGCGCTTGAGCTCTCTGGAAAAAGAATAGCAAGAAAAGGCTATGAAGTTTTAAAG AATGGAGAGAGAGTGGGAGAGATCACAAGTGGTAACTTCTCTCCAACTCTTGGGAAGTCG ATAGCGCTGGCTCTCGTTTCAAAATCGGTGAAGATAGGAGACCAACTGGGAGTGGTGTTT CCTGGTGGAAAGCTTGTAGAAGCTCTGGTAGTAAAAAAACCATTTTACAGAGGCAGTGTG AGGAGGGAGGTTTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9WY54 UniProtKB Entry Name GCST_THEMA GenBank Protein ID 4980708 GenBank Gene ID AE000512 PDB ID(s) 1WOO, 1WOP, 1WOR, 1WOS KEGG ID tma:TM0211 NCBI Gene ID 897085 - General References
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details (6R)-Folinic acid experimental unknown target Details Dihydrolipoic Acid experimental unknown target Details