Molybdenum cofactor guanylyltransferase

BE0001693ProteinEscherichia coli (strain K12)mobA

Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. It is acted on by 1 drug in DrugBank.

Gene name
mobA
UniProtKB entry
P32173Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
194 residues · 21,643 Da
Also known as
2.7.7.77 · chlB · GTP:molybdopterin guanylyltransferase · MGD synthase · Mo-MPT guanylyltransferase

Resolves to

Protein
UniProtP32173UniProt nameMOBA_ECOLI
Gene
NCBI Gene948349GenBank304962
Pharmacology
KEGGecj:JW3829
Structure
PDB1E5KPDB1FR9PDB1FRW
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Molybdenum cofactor guanylyltransferase, and which indications are they being tested in?

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