Nicotinate-nucleotide adenylyltransferase

BE0001695ProteinBacillus subtilis (strain 168)nadD

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). It is acted on by 1 drug in DrugBank.

Gene name
nadD
UniProtKB entry
P54455Swiss-Prot
Residues / weight
189 residues · 22,156 Da
Also known as
2.7.7.18 · Deamido-NAD(+) diphosphorylase · Deamido-NAD(+) pyrophosphorylase · NaMN adenylyltransferase · Nicotinate mononucleotide adenylyltransferase

Resolves to

Protein
UniProtP54455UniProt nameNADD_BACSU
Gene
NCBI Gene937818GenBank1303791
Pharmacology
KEGGbsu:BSU25640
Structure
PDB1KAMPDB1KAQ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nicotinate-nucleotide adenylyltransferase, and which indications are they being tested in?

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