Tryptophan synthase alpha chain

BE0001719ProteinThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)trpA

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. It is acted on by 1 drug in DrugBank.

Gene name
trpA
UniProtKB entry
P16608Swiss-Prot
Residues / weight
271 residues · 28,936 Da
Also known as
4.2.1.20

Resolves to

Protein
UniProtP16608UniProt nameTRPA_THET2
Gene
GenBank155133
Pharmacology
KEGGtth:TTC0729
Structure
PDB1UJPPDB1WXJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tryptophan synthase alpha chain, and which indications are they being tested in?

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