Ribosome-recycling factor

Details

Name
Ribosome-recycling factor
Kind
protein
Synonyms
  • Ribosome-releasing factor
  • RRF
Gene Name
frr
UniProtKB Entry
P0A808Swiss-Prot
Organism
Shigella flexneri
NCBI Taxonomy ID
623
Amino acid sequence
>lcl|BSEQ0011230|Ribosome-recycling factor
MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVE
DSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGE
AEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEA
ELMQF
Number of residues
185
Molecular Weight
20638.31
Theoretical pI
6.88
GO Classification
Processes
translational termination
Components
cytoplasm
General Function
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
Specific Function
ribosomal large subunit binding
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
>lcl|BSEQ0011231|Ribosome-recycling factor (frr)
GTGATTAGCGATATCAGAAAAGATGCTGAAGTACGCATGGACAAATGCGTAGAAGCGTTC
AAAACCCAAATCAGCAAAATACGCACGGGTCGTGCTTCTCCCAGCCTGCTGGATGGCATT
GTCGTGGAATATTACGGCACGCCGACGCCGCTGCGTCAGCTGGCAAGCGTAACGGTAGAA
GATTCCCGTACTCTGAAAATCAACGTGTTTGATCGTTCAATGTCTCCGGCCGTTGAAAAA
GCGATTATGGCCTCCGATCTCGGCCTGAACCCGAACTCTGCGGGTAGCGACATCCGTGTT
CCGCTGCCGCCGCTGACGGAAGAACGTCGTAAAGATCTGACCAAAATCGTTCGTGGTGAA
GCAGAACAAGCGCGTGTTGCAGTACGTAATGTGCGTCGTGACGCGAACGACAAAGTGAAA
GCACTGTTGAAAGATAAAGAGATCAGCGAAGACGACGATCGCCGTTCTCAGGACGATGTA
CAGAAACTGACTGATGCTGCAATCAAGAAAATTGAAGCGGCGCTGGCAGACAAAGAAGCA
GAACTGATGCAGTTCTGA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP0A808
UniProtKB Entry NameRRF_SHIFL
GenBank Protein ID24050375
GenBank Gene IDAE005674
KEGG IDsfl:SF0162
NCBI Gene ID1024426
General References
  1. Jin Q, Yuan Z, Xu J, Wang Y, Shen Y, Lu W, Wang J, Liu H, Yang J, Yang F, Zhang X, Zhang J, Yang G, Wu H, Qu D, Dong J, Sun L, Xue Y, Zhao A, Gao Y, Zhu J, Kan B, Ding K, Chen S, Cheng H, Yao Z, He B, Chen R, Ma D, Qiang B, Wen Y, Hou Y, Yu J: Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 2002 Oct 15;30(20):4432-41. [Article]
  2. Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett G 3rd, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR: Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun. 2003 May;71(5):2775-86. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Decyloxy-MethanolexperimentalunknowntargetDetails