3-dehydroquinate dehydratase

BE0001743ProteinHelicobacter pylori (strain ATCC 700392 / 26695)aroQ

Catalyzes a trans-dehydration via an enolate intermediate. It is acted on by 2 drugs in DrugBank.

Gene name
aroQ
UniProtKB entry
Q48255Swiss-Prot
Residues / weight
167 residues · 18,483 Da
Also known as
3-dehydroquinase · 4.2.1.10 · Type II DHQase

Resolves to

Protein
UniProtQ48255UniProt nameAROQ_HELPY
Gene
NCBI Gene899573GenBank2314182
Pharmacology
KEGGheo:C694_05370
Structure
PDB1J2YPDB2C4VPDB2C4W
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-dehydroquinate dehydratase, and which indications are they being tested in?

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