Glucosamine-6-phosphate deaminase 1

BE0001752ProteinBacillus subtilis (strain 168)nagB

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. It is acted on by 2 drugs in DrugBank.

Gene name
nagB
UniProtKB entry
O35000Swiss-Prot
Residues / weight
242 residues · 26,991 Da
Also known as
3.5.99.6 · GlcN6P deaminase 1 · Glucosamine-6-phosphate isomerase 1 · GNPDA 1

Resolves to

Protein
UniProtO35000UniProt nameNAGB_BACSU
Gene
NCBI Gene936619GenBank2618855
Pharmacology
KEGGbsu:BSU35020
Structure
PDB2BKVPDB2BKX
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glucosamine-6-phosphate deaminase 1, and which indications are they being tested in?

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