Serine hydroxymethyltransferase

BE0001753ProteinGeobacillus kaustophilus (strain HTA426)glyA

Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. It is acted on by 1 drug in DrugBank.

Gene name
glyA
UniProtKB entry
Q5KUI2Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
412 residues · 45,175 Da
Also known as
2.1.2.1 · SHMT

Resolves to

Protein
UniProtQ5KUI2UniProt nameGLYA_GEOKA
Gene
NCBI Gene3183576GenBank56381746
Pharmacology
KEGGgka:GK3369
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Serine hydroxymethyltransferase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In