Isocitrate lyase

BE0001761ProteinMycobacterium tuberculosisicl

Involved in the persistence and virulence of M.tuberculosis. It is acted on by 1 drug in DrugBank.

Gene name
icl
UniProtKB entry
P9WKK7Swiss-Prot
Residues / weight
428 residues · 47,086 Da
Also known as
4.1.3.1 · ICL · Isocitrase · Isocitratase

Resolves to

Protein
UniProtP9WKK7UniProt nameACEA_MYCTU
Gene
NCBI Gene886291
Pharmacology
KEGGmtu:Rv0467
Structure
PDB1F61PDB1F8IPDB1F8M
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Isocitrate lyase, and which indications are they being tested in?

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