Enoyl-CoA delta isomerase 1, mitochondrial

BE0001764ProteinHumansECI1

Auxiliary enzyme in the beta-oxidation of mono- and polyunsaturated fatty acids (PubMed:26474213, PubMed:7818490). It is acted on by 2 drugs in DrugBank.

Gene name
ECI1
UniProtKB entry
P42126Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
302 residues · 32,816 Da
Also known as
3,2-trans-enoyl-CoA isomerase · 5.3.3.8 · D3,D2-enoyl-CoA isomerase · DCI · Delta(3),Delta(2)-enoyl-CoA isomerase

Resolves to

Protein
UniProtP42126UniProt nameECI1_HUMAN
Gene
HGNCHGNC:2703NCBI Gene1632GenBank472987GeneCardsECI1
Pharmacology
KEGGhsa:1632
Structure
PDB1SG4
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Enoyl-CoA delta isomerase 1, mitochondrial, and which indications are they being tested in?

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