Intracellular exo-alpha-(1->5)-L-arabinofuranosidase

BE0001766ProteinGeobacillus stearothermophilusabfA

Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. It is acted on by 2 drugs in DrugBank.

Gene name
abfA
UniProtKB entry
Q9XBQ3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
502 residues · 57,212 Da
Also known as
3.2.1.55 · ABF · Arabinosidase · Intracellular arabinan exo-alpha-(1->5)-L-arabinosidase

Resolves to

Protein
UniProtQ9XBQ3UniProt nameIABF_GEOSE
Gene
GenBank16767843
Structure
PDB1PZ2PDB1PZ3PDB1QW8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Intracellular exo-alpha-(1->5)-L-arabinofuranosidase, and which indications are they being tested in?

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