NH(3)-dependent NAD(+) synthetase

BE0001768ProteinHelicobacter pylori (strain ATCC 700392 / 26695)nadE

Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. It is acted on by 1 drug in DrugBank.

Gene name
nadE
UniProtKB entry
O25096Swiss-Prot
Residues / weight
260 residues · 29,269 Da
Also known as
6.3.1.5

Resolves to

Protein
UniProtO25096UniProt nameNADE_HELPY
Gene
NCBI Gene900366GenBank2313426
Pharmacology
KEGGheo:C694_01665
Structure
PDB1XNGPDB1XNH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on NH(3)-dependent NAD(+) synthetase, and which indications are they being tested in?

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