3-dehydroquinate dehydratase

BE0001769ProteinStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)aroQ

Catalyzes a trans-dehydration via an enolate intermediate. It is acted on by 5 drugs in DrugBank.

Gene name
aroQ
UniProtKB entry
P15474Swiss-Prot
Residues / weight
157 residues · 16,682 Da
Also known as
3-dehydroquinase · 4.2.1.10 · Type II DHQase

Resolves to

Protein
UniProtP15474UniProt nameAROQ_STRCO
Gene
NCBI Gene1097395GenBank2558614
Pharmacology
KEGGsco:SCO1961
Structure
PDB1D0IPDB1GTZPDB1GU0
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
14+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 3-dehydroquinate dehydratase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In