Ribonucleoside-diphosphate reductase 2 subunit alpha

BE0001782ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)nrdE

Provides the precursors necessary for DNA synthesis. It is acted on by 3 drugs in DrugBank.

Gene name
nrdE
UniProtKB entry
Q08698Swiss-Prot
Residues / weight
714 residues · 80,587 Da
Also known as
1.17.4.1 · R1E protein · Ribonucleotide reductase 2

Resolves to

Protein
UniProtQ08698UniProt nameRIR3_SALTY
Gene
NCBI Gene1254330GenBank1050838
Pharmacology
KEGGstm:STM2807
Structure
PDB1PEMPDB1PEOPDB1PEQ
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ribonucleoside-diphosphate reductase 2 subunit alpha, and which indications are they being tested in?

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