Genome polyprotein

BE0001791ProteinBVDV

N-terminal protease Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. It is acted on by 1 drug in DrugBank.

UniProtKB entry
P19711Swiss-Prot
Cellular location
Host membrane
Residues / weight
3,988 residues · 449,159 Da
Also known as
3.4.22.- · N-pro

Resolves to

Protein
UniProtP19711UniProt namePOLG_BVDVN
Gene
NCBI Gene1489735GenBank323206
Pharmacology
KEGGvg:1489735
Structure
PDB1S48PDB1S49PDB1S4F
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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27GO termsFunction, process and component, as structured annotations
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9Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Genome polyprotein, and which indications are they being tested in?

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