Histidine--tRNA ligase

BE0001795ProteinEscherichia coli (strain K12)hisS

Histidine--tRNA ligase (Escherichia coli (strain K12)) is a protein target in DrugBank. It is acted on by 2 drugs in DrugBank.

Gene name
hisS
UniProtKB entry
P60906Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
424 residues · 47,029 Da
Also known as
6.1.1.21 · HisRS · Histidyl-tRNA synthetase

Resolves to

Protein
UniProtP60906UniProt nameSYH_ECOLI
Gene
NCBI Gene946989GenBank146372
Pharmacology
KEGGecj:JW2498
Structure
PDB1HTTPDB1KMMPDB1KMN
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Histidine--tRNA ligase, and which indications are they being tested in?

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