Deoxyribose-phosphate aldolase

BE0001797ProteinEscherichia coli (strain K12)deoC

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed:11598300, PubMed:17905878, PubMed:6749498). It is acted on by 1 drug in DrugBank.

Gene name
deoC
UniProtKB entry
P0A6L0Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
259 residues · 27,733 Da
Also known as
2-deoxy-D-ribose 5-phosphate aldolase · 4.1.2.4 · Deoxyriboaldolase · DERA · dra

Resolves to

Protein
UniProtP0A6L0UniProt nameDEOC_ECOLI
Gene
NCBI Gene948902GenBank41252
Pharmacology
KEGGecj:JW4344
Structure
PDB1JCJPDB1JCLPDB1KTN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Deoxyribose-phosphate aldolase, and which indications are they being tested in?

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