PTS system N,N'-diacetylchitobiose-specific EIIB component

BE0001803ProteinEscherichia coli (strain K12)chbB

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. It is acted on by 1 drug in DrugBank.

Gene name
chbB
UniProtKB entry
P69795Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
106 residues · 11,426 Da
Also known as
2.7.1.69 · celA · EIIB-Chb · IVcel · N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component

Resolves to

Protein
UniProtP69795UniProt namePTQB_ECOLI
Gene
NCBI Gene945339GenBank41097
Pharmacology
KEGGecj:JW1727
Structure
PDB1E2BPDB1H9CPDB1IIB
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on PTS system N,N'-diacetylchitobiose-specific EIIB component, and which indications are they being tested in?

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