Xanthine phosphoribosyltransferase

BE0001812ProteinBacillus subtilis (strain 168)xpt

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis. It is acted on by 1 drug in DrugBank.

Gene name
xpt
UniProtKB entry
P42085Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
194 residues · 21,038 Da
Also known as
2.4.2.22 · XPRTase

Resolves to

Protein
UniProtP42085UniProt nameXPT_BACSU
Gene
NCBI Gene939064GenBank633169
Pharmacology
KEGGbsu:BSU22070
Structure
PDB1Y0BPDB2FXV
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Xanthine phosphoribosyltransferase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In