Early endosome antigen 1

BE0001815ProteinHumansEEA1

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. It is acted on by 1 drug in DrugBank.

Gene name
EEA1
UniProtKB entry
Q15075Swiss-Prot
Cellular location
Early endosome membrane
Residues / weight
1,411 residues · 162,465 Da
Also known as
Endosome-associated protein p162 · ZFYVE2 · Zinc finger FYVE domain-containing protein 2

Resolves to

Protein
UniProtQ15075UniProt nameEEA1_HUMAN
Gene
HGNCHGNC:3185NCBI Gene8411GenBank1016368GeneCardsEEA1
Pharmacology
KEGGhsa:8411
Structure
PDB1HYIPDB1HYJPDB1JOC
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Early endosome antigen 1, and which indications are they being tested in?

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