Serpin B5

BE0001845ProteinHumansSERPINB5

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. It is acted on by 1 drug in DrugBank.

Gene name
SERPINB5
UniProtKB entry
P36952Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
375 residues · 42,100 Da
Also known as
Maspin · Peptidase inhibitor 5 · PI-5 · PI5

Resolves to

Protein
UniProtP36952UniProt nameSPB5_HUMAN
Gene
HGNCHGNC:8949NCBI Gene5268GenBank453369GeneCardsSERPINB5
Pharmacology
KEGGhsa:5268
Structure
PDB1WZ9PDB1XQGPDB1XQJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Serpin B5, and which indications are they being tested in?

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