Macrophage migration inhibitory factor

BE0001855ProteinHumansMIF

Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens (PubMed:15908412, PubMed:17443469, PubMed:23776208). It is acted on by 11 drugs in DrugBank.

Gene name
MIF
UniProtKB entry
P14174Swiss-Prot
Cellular location
Secreted
Residues / weight
115 residues · 12,476 Da
Also known as
5.3.2.1 · GIF · GLIF · Glycosylation-inhibiting factor · L-dopachrome isomerase

Resolves to

Protein
UniProtP14174UniProt nameMIF_HUMAN
Gene
HGNCHGNC:7097NCBI Gene4282GenBank188556GeneCardsMIF
Pharmacology
KEGGhsa:4282
Structure
PDB1CA7PDB1CGQPDB1GCZ
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
16GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
59+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Macrophage migration inhibitory factor, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In