3-dehydroquinate dehydratase

BE0001857ProteinMycobacterium tuberculosisaroQ

Catalyzes a trans-dehydration via an enolate intermediate. It is acted on by 2 drugs in DrugBank.

Gene name
aroQ
UniProtKB entry
P9WPX7Swiss-Prot
Residues / weight
147 residues · 15,790 Da
Also known as
3-dehydroquinase · 4.2.1.10 · aroD · Type II DHQase

Resolves to

Protein
UniProtP9WPX7UniProt nameAROQ_MYCTU
Gene
NCBI Gene888397
Pharmacology
KEGGmtu:Rv2537c
Structure
PDB1H05PDB1H0RPDB1H0S
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-dehydroquinate dehydratase, and which indications are they being tested in?

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