Histidine--tRNA ligase

BE0001860ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)hisS

Histidine--tRNA ligase (Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)) is a protein target in DrugBank. It is acted on by 1 drug in DrugBank.

Gene name
hisS
UniProtKB entry
P56194Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
421 residues · 47,041 Da
Also known as
6.1.1.21 · HisRS · Histidyl-tRNA synthetase

Resolves to

Protein
UniProtP56194UniProt nameSYH_THET8
Gene
NCBI Gene3168691GenBank55772094
Pharmacology
KEGGttj:TTHA0712
Structure
PDB1ADJPDB1ADY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Histidine--tRNA ligase, and which indications are they being tested in?

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