Cytosine deaminase

BE0001862ProteinEscherichia coli (strain K12)codA

Catalyzes the hydrolytic deamination of cytosine to uracil. It is acted on by 3 drugs in DrugBank.

Gene name
codA
UniProtKB entry
P25524Swiss-Prot
Residues / weight
427 residues · 47,591 Da
Also known as
3.5.4.1 · CD · Cytosine aminohydrolase · Isoguanine deaminase

Resolves to

Protein
UniProtP25524UniProt nameCODA_ECOLI
Gene
NCBI Gene944996GenBank581051
Pharmacology
KEGGecj:JW0328
Structure
PDB1K6WPDB1K70PDB1R9X
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cytosine deaminase, and which indications are they being tested in?

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