Exotoxin A

BE0001869ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)eta

An NAD-dependent ADP-ribosyltransferase (ADPRT). It is acted on by 2 drugs in DrugBank.

Gene name
eta
UniProtKB entry
P11439Swiss-Prot
Residues / weight
638 residues · 69,283 Da
Also known as
2.4.2.36 · ETA · NAD(+)--diphthamide ADP-ribosyltransferase · PE · Pseudomonas exotoxin

Resolves to

Protein
UniProtP11439UniProt nameTOXA_PSEAE
Gene
NCBI Gene877850GenBank151216
Pharmacology
KEGGpae:PA1148
Structure
PDB1AERPDB1DMAPDB1IKP
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Exotoxin A, how selective are they, and which programs against it are still in active trials?

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