Arsenate reductase

BE0001876ProteinStaphylococcus aureusarsC

Catalyzes the reduction of arsenate [As(V)] to arsenite As(III) (PubMed:10606519, PubMed:11862551, PubMed:12072565, PubMed:12682056, PubMed:1409657, PubMed:16797027, PubMed:8003493). It is acted on by 3 drugs in DrugBank.

Gene name
arsC
UniProtKB entry
P0A006Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
131 residues · 14,813 Da
Also known as
1.20.4.4 · Arsenical pump modifier · Low molecular weight protein-tyrosine-phosphatase · Protein ArsC

Resolves to

Protein
UniProtP0A006UniProt nameARSC_STAAU
Gene
NCBI Gene13874340GenBank150729
Pharmacology
KEGGpg:13874340
Structure
PDB1JF8PDB1JFVPDB1LJL
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Arsenate reductase, and which indications are they being tested in?

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