Glutamine synthetase

BE0001881ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)glnA

Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. It is acted on by 1 drug in DrugBank.

Gene name
glnA
UniProtKB entry
P0A1P6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
469 residues · 51,785 Da
Also known as
6.3.1.2 · Glutamate--ammonia ligase · Glutamine synthetase I beta · GS · GSI beta

Resolves to

Protein
UniProtP0A1P6UniProt nameGLN1B_SALTY
Gene
NCBI Gene1255533GenBank154090
Pharmacology
KEGGstm:STM4007
Structure
PDB1F1HPDB1F52PDB1FPY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glutamine synthetase, and which indications are they being tested in?

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