Putative DD-carboxypeptidase TP_0574

BE0001895ProteinTreponema pallidum (strain Nichols)

A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus (PubMed:12196546, PubMed:7972112). It is acted on by 1 drug in DrugBank.

UniProtKB entry
P29723Swiss-Prot
Cellular location
Cell membrane
Residues / weight
434 residues · 47,665 Da
Also known as
3.4.-.- · 47 kDa lipoprotein · 47 kDa membrane antigen · 47 kDa membrane antigen precursor · 47-kilodalton major integral membrane immunogen

Resolves to

Protein
UniProtP29723UniProt nameTA47_TREPA
Gene
NCBI Gene2611716GenBank155053
Pharmacology
KEGGtpa:TP_0574
Structure
PDB1O75
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Putative DD-carboxypeptidase TP_0574, and which indications are they being tested in?

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