Glucose-1-phosphate thymidylyltransferase

BE0001910ProteinSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)rmlA

Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. It is acted on by 2 drugs in DrugBank.

Gene name
rmlA
UniProtKB entry
P26393Swiss-Prot
Residues / weight
292 residues · 32,453 Da
Also known as
2.7.7.24 · dTDP-glucose pyrophosphorylase · dTDP-glucose synthase · Ep · rfbA

Resolves to

Protein
UniProtP26393UniProt nameRMLA_SALTY
Gene
NCBI Gene1253616GenBank47891
Pharmacology
KEGGstm:STM2095
Structure
PDB1IIMPDB1IINPDB1MP3
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glucose-1-phosphate thymidylyltransferase, and which indications are they being tested in?

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