Glucose-1-phosphate thymidylyltransferase 2

BE0001912ProteinShigella flexnerirffH

Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. It is acted on by 1 drug in DrugBank.

Gene name
rffH
UniProtKB entry
P61888Swiss-Prot
Residues / weight
293 residues · 32,734 Da
Also known as
2.7.7.24 · dTDP-glucose pyrophosphorylase 2 · dTDP-glucose synthase 2 · rmlA2

Resolves to

Protein
UniProtP61888UniProt nameRMLA2_SHIFL
Gene
NCBI Gene1025982GenBank24054349
Pharmacology
KEGGsfl:SF3863
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Glucose-1-phosphate thymidylyltransferase 2, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In