Uracil-DNA glycosylase

BE0001925ProteinEscherichia coli O157:H7ung

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. It is acted on by 1 drug in DrugBank.

Gene name
ung
UniProtKB entry
Q8X444Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
229 residues · 25,662 Da
Also known as
3.2.2.27 · UDG

Resolves to

Protein
UniProtQ8X444UniProt nameUNG_ECO57
Gene
GenBank12517001
Pharmacology
KEGGece:Z3864
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Uracil-DNA glycosylase, and which indications are they being tested in?

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