Thymidine kinase

BE0001929ProteinEHV-4TK

Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. It is acted on by 1 drug in DrugBank.

Gene name
TK
UniProtKB entry
P24425Swiss-Prot
Residues / weight
352 residues · 38,784 Da
Also known as
2.7.1.21

Resolves to

Protein
UniProtP24425UniProt nameKITH_EHV4
Gene
GenBank221822
Structure
PDB1P6XPDB1P72PDB1P73
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thymidine kinase, and which indications are they being tested in?

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