Thymidylate kinase

BE0001932ProteinShigella flexneritmk

Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. It is acted on by 1 drug in DrugBank.

Gene name
tmk
UniProtKB entry
P0A721Swiss-Prot
Residues / weight
213 residues · 23,783 Da
Also known as
2.7.4.9 · dTMP kinase · Thymidine monophosphate kinase · TMPK

Resolves to

Protein
UniProtP0A721UniProt nameKTHY_SHIFL
Gene
NCBI Gene1024058GenBank24051392
Pharmacology
KEGGsfl:SF1102
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thymidylate kinase, and which indications are they being tested in?

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