Lactose permease

BE0001939ProteinEscherichia coli (strain K12)lacY

Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system). It is acted on by 2 drugs in DrugBank.

Gene name
lacY
UniProtKB entry
P02920Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
417 residues · 46,503 Da
Also known as
Lactose-proton symport

Resolves to

Protein
UniProtP02920UniProt nameLACY_ECOLI
Gene
NCBI Gene949083GenBank146578
Pharmacology
KEGGecj:JW0334
Structure
PDB1M2UPDB1PV6PDB1PV7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Lactose permease, and which indications are they being tested in?

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