1-phosphatidylinositol phosphodiesterase

BE0001955ProteinBacillus cereus

Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. It is acted on by 2 drugs in DrugBank.

UniProtKB entry
P14262Swiss-Prot
Cellular location
Secreted
Residues / weight
329 residues · 38,109 Da
Also known as
4.6.1.13 · Phosphatidylinositol diacylglycerol-lyase · Phosphatidylinositol-specific phospholipase C · PI-PLC

Resolves to

Protein
UniProtP14262UniProt namePLC_BACCE
Gene
GenBank143340
Structure
PDB1GYMPDB1PTDPDB1PTG
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 1-phosphatidylinositol phosphodiesterase, and which indications are they being tested in?

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