Phosphopantetheine adenylyltransferase

BE0001958ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)coaD

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. It is acted on by 1 drug in DrugBank.

Gene name
coaD
UniProtKB entry
Q9WZK0Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
161 residues · 18,249 Da
Also known as
2.7.7.3 · Dephospho-CoA pyrophosphorylase · kdtB · Pantetheine-phosphate adenylyltransferase · PPAT

Resolves to

Protein
UniProtQ9WZK0UniProt nameCOAD_THEMA
Gene
NCBI Gene898408GenBank4981265
Pharmacology
KEGGtma:TM0741
Structure
PDB1VLH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphopantetheine adenylyltransferase, and which indications are they being tested in?

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