Peroxiredoxin-2

BE0001972ProteinHumansPRDX2

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. It is acted on by 3 drugs in DrugBank.

Gene name
PRDX2
UniProtKB entry
P32119Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
198 residues · 21,892 Da
Also known as
1.11.1.24 · Natural killer cell-enhancing factor B · NKEF-B · NKEFB · PRP

Resolves to

Protein
UniProtP32119UniProt namePRDX2_HUMAN
Gene
HGNCHGNC:9353NCBI Gene7001GenBank438069GeneCardsPRDX2
Pharmacology
KEGGhsa:7001
Structure
PDB1QMVPDB5B8APDB5B8B
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peroxiredoxin-2, how selective are they, and which programs against it are still in active trials?

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