Antitumor antibiotic C-1027 apoprotein

BE0001994ProteinStreptomyces globisporuscagA

Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. It is acted on by 1 drug in DrugBank.

Gene name
cagA
UniProtKB entry
Q06110Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
143 residues · 13,873 Da
Also known as
C-1027-AG

Resolves to

Protein
UniProtQ06110UniProt nameCAGA_STRGL
Gene
GenBank217003
Structure
PDB1HZKPDB1HZLPDB1J48
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Antitumor antibiotic C-1027 apoprotein, and which indications are they being tested in?

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